Quinolone antibiotics and Iron preparations
Posted on September 1, 2009
Some preliminary evidence shows that iron preparations can reduce the absorption of cipro and ofloxacin front the gut. The auinolone-iron complexes formed have reduced antibacterial effects.
Clinical evidence
A cross-over trial in 12 normal subjects given single doses of 500 mg cipro or 400 mg ofloxacin showed that the concurrent use of 200 mg iron (in the form of an rron-glycine-sulphate complex) reduced the bioavailability of the cipro by 48% and that of ofloxacin by 36%. Another study found that 325 mg ferrous sulphate three times a day reduced the absorption of cipro in normal subjects by 65%. Reduced serum levels of cipro (peak levels reduced from 5 2 to 0.3-0.5) were recorded in another patient while taking ferrous sulphate.
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Tags: Antibiotics, cipro
The Side Effects of Antibiotics and How to Avoid It Posted By : E B Ezidiegwu
Posted on January 6, 2009
Combating known side effects of antibiotics: When the body is overwhelmed by a bacterial infection like tuberculosis, syphilis, or meningitis, antibiotics can be used to help the bodys white blood cells make your body healthy once again. However, in some cases, antibiotic-medicines have very dangerous side effects. If you use any kind of medicine while you are sick, it is important to talk to your doctor about the side effects you can expect. The body already makes natural antibiotics through the immune system. Called antibodies, in many cases, these natural antibiotics are all your body needs to fight bacteria in the body. Many times, you wont even experience symptoms. Prescription antibiotics are only needed when the bodys natural-antibiotics arent strong enough to ward off infections.
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